If heart disease runs in your family, start exercising now

If heart disease runs in your family, start exercising now

Genetic data from 468,095 of the participants was also used in the study.

She added: "Prior to their breast cancer diagnosis, some women may already have undiagnosed coronary heart disease, increasing their risk of a heart attack and subsequent heart failure".

In particular, high levels of cardiorespiratory fitness were associated with 49% lower risk for coronary heart disease (HR, 0.51; 95% CI, 0.38-0.69) and 60% lower risk for atrial fibrillation (HR, 0.40; 95%, CI 0.30-0.55) among individuals at high genetic risk for these diseases.

"It is particularly good news for the large number of affected patients that if they are in good medical care and have survived breast cancer, they do not need to be more anxious about deadly heart diseases than women at the same age without breast cancer". The researchers measured physical activity through fitness monitors.

Physical fitness cuts risk of heart disease including heart attacks and stroke, a new, large study suggests.

A paper describing the research was published online April 9 in Circulation. The new study is one of the first to look at how exercise might help a person with a family risk of heart disease keep complications at bay.

For participants with an intermediate genetic risk for cardiovascular diseases, it was revealed that those with the strongest grips were 36 per cent less likely to develop coronary heart disease and had a 46 per cent reduction in their risk for atrial fibrillation, compared to study participants with the same genetic risk who had the weakest grips.

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The International Physical Activity Questionnaire was used to assess self-reported exercise, while wrist-worn accelerometers, hand dynamometers (grip strength) and submaximal exercise treadmill were used for objective measures.

The study comes with several important caveats. The authors noted that "we can't definitely claim a causal connection", as observational studies are created to establish trends.

Given whatever little is known about the risk-modifying effects of exercise in numerous individuals who come with increased genetic risk of cardiovascular disease, these findings could have important ramifications on the public health, as the said study concludes.

The results were adjusted for age, gender, ethnicity, region, socioeconomic status, diabetes, smoking, systolic blood pressure, body mass index and use of lipid medications.

"We regard the result of our study as very positive for the treatment of breast cancer", summarizes Brenner.

Erik Ingelsson, MD, PhD, professor of cardiovascular medicine, said that people should not give up exercising as they come with a high genetic risk for heart disease and even if one does not have such high genetic risk, nevertheless, one should not stop exercising. However, for any individual, Dr. Ingelsson advised that "it would be best to discuss a physical activity plan with a physician".

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